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In order to conserve the limited bandwidth available .iso images are not downloadable from mirror.centos.org

The following mirrors should have the ISO images available:

http://mirror.ubiquityservers.com/centos/5.10/isos/x86_64/
http://mirrors.greenmountainaccess.net/centos/5.10/isos/x86_64/
http://centos.arvixe.com/5.10/isos/x86_64/
http://mirror.umd.edu/centos/5.10/isos/x86_64/
http://mirror.millry.co/CentOS/5.10/isos/x86_64/
http://mirror.es.its.nyu.edu/centos/5.10/isos/x86_64/
http://centos-mirror.jchost.net/5.10/isos/x86_64/
http://mirrors.gigenet.com/centos/5.10/isos/x86_64/
http://mirror.acsnet.com/centos/5.10/isos/x86_64/
http://mirrordenver.fdcservers.net/centos/5.10/isos/x86_64/
http://mirror.compevo.com/centos/5.10/isos/x86_64/
http://mirrors.adams.net/centos/5.10/isos/x86_64/
http://holmes.umflint.edu/centos/5.10/isos/x86_64/
http://repo.dimenoc.com/pub/centos/5.10/isos/x86_64/
http://ftp.linux.ncsu.edu/pub/CentOS/5.10/isos/x86_64/
http://mirror.team-cymru.org/CentOS/5.10/isos/x86_64/
http://www.gtlib.gatech.edu/pub/centos/5.10/isos/x86_64/

Mirrors Verified Tue Sep 23 14:12:59 2014 UTC

Or use bittorrent to download the .torrent files provided.

Bittorrent is a peer to peer download system described at http://bittorrent.com/ and there are many clients available.

These include (in no particular order of preference): utorrent, vuze (Azureus), BitTorrent, Deluge, ctorrent, ktorrent, rtorrent and transmission.

Packaged copies of various torrent clients for CentOS can be found in the repositories listed in the following wiki article : http://wiki.centos.org/AdditionalResources/Repositories